A.  The most important thing for you to do is to lay very still.  Ask your physician to let you know when he is going to aspirate the marrow (watch the video).  At that moment you may  experience slight discomfort or momentary pain that may only last a couple of seconds.  The best thing to do is to hold your breath for those few seconds or to count backwards from 20 to 1 while the biopsy is being obtained.